Status:

COMPLETED

The Effect of Proton Pump Inhibitors on Calcium and Bone Metabolism

Lead Sponsor:

American University of Beirut Medical Center

Collaborating Sponsors:

AstraZeneca

Conditions:

Calcium Metabolism Disorders

Eligibility:

MALE

18-50 years

Phase:

NA

Brief Summary

This prospective, single-blind, matched controlled study aims to evaluate the effect of proton pump inhibitors on biochemical markers of calcium and bone metabolism in an effort to establish additiona...

Eligibility Criteria

Inclusion

  • Males aged 18-50 years
  • Healthy (or healthy with heartburn only)

Exclusion

  • Female gender
  • Previous allergy to PPI
  • Regular beach seekers (more than once a week)
  • Intestinal disease
  • Recent fracture (within the past six months)
  • Kidney stones
  • Intake of the following medications:
  • Vitamin D or calcium supplements
  • PPIs or H2 receptor antagonists within the past year
  • One-Alpha
  • Anticonvulsants
  • Glucocorticoids

Key Trial Info

Start Date :

October 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2010

Estimated Enrollment :

58 Patients enrolled

Trial Details

Trial ID

NCT01139645

Start Date

October 1 2009

End Date

July 1 2010

Last Update

January 28 2013

Active Locations (1)

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American University of Beirut - Medical Center

Beirut, Lebanon