Status:
TERMINATED
Use of Transdermal Clonidine in Trauma Patients
Lead Sponsor:
Memorial Health University Medical Center
Conditions:
Delirium
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This study will attempt to learn how to better treat trauma patients with delirium who are on a breathing machine. Delirium, also known as acute, temporary brain dysfunction, is a common reason why ve...
Detailed Description
Obtaining the appropriate level of sedation and analgesia in severely injured trauma patients admitted to the intensive care unit (ICU) can be challenging due to the diversity of injuries as well as t...
Eligibility Criteria
Inclusion
- Ventilated male or female trauma patient 18 years of age or older admitted to the ICU \>24 hours
- Patient must meet minimal medical criteria for potential extubation (meet criteria for being placed on spontaneous breathing trials per established MUMC SBT protocol)
- Patients must exhibit delirium as assessed by the CAM-ICU assessment tool
- Patient must be declared stable from a neurologic, respiratory and cardiovascular standpoint to receive clonidine by the attending MD
- Consent must be obtained prior to any study procedures
Exclusion
- Patient \< 18 years old
- Bradycardia (HR \< 60)
- Presence of active pacemaker
- Hypotensive (\<90/60)or active treatment of hypotension with vasoactive medications
- Patient actively being treated with Clonidine or dexmedetomidine
- Presence of allergy to Clonidine
- Pregnancy
Key Trial Info
Start Date :
May 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2012
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT01139996
Start Date
May 1 2010
End Date
August 1 2012
Last Update
June 14 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Memorial Health University Medical Center
Savannah, Georgia, United States, 31404