Status:
TERMINATED
Cerebral Metabolic Changes Associated With Thalamic Stimulation
Lead Sponsor:
The Hospital for Sick Children
Collaborating Sponsors:
University Health Network, Toronto
Conditions:
Epilepsy
Eligibility:
All Genders
18-85 years
Phase:
PHASE3
Brief Summary
The purpose of this research study is to evaluate the brain circuits function and circuits involved in the mechanism of thalamic DBS in patients with medically refractory epilepsy.
Detailed Description
Deep brain stimulation (DBS) of the anterior nucleus of the thalamus in patients with medically refractory epilepsy has been shown to be efficacious. Studies have estimated a 46-76% reduction in seizu...
Eligibility Criteria
Inclusion
- 18-85 years old
- currently have DBS implanted for medically refractory epilepsy
- Women of childbearing age will be required to use established contraceptive methods while enrolled in the study.
Exclusion
- Patients who:
- are \< 18 years of age or \> 85 years of age
- are medically unstable
- are women who are potentially pregnant, pregnant or nursing
- have had PET imaging within 1 year.
Key Trial Info
Start Date :
March 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2014
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT01141764
Start Date
March 1 2010
End Date
February 1 2014
Last Update
November 21 2014
Active Locations (2)
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1
The Hospital for Sick Children
Toronto, Ontario, Canada, M5G 1X8
2
Toronto Western Hospital
Toronto, Ontario, Canada, M5T 2S8