Status:
COMPLETED
T-Cell Project: Prospective Collection of Data in Patients With Peripheral T-Cell Lymphoma
Lead Sponsor:
Associazione Angela Serra per la ricerca sul cancro
Collaborating Sponsors:
Fondazione Italiana Linfomi - ETS
INTERNATIONAL T-CELL NON-HODGKIN'S LYMPHOMA STUDY GROUP
Conditions:
Lymphoma, T-Cell, Peripheral
Eligibility:
All Genders
18+ years
Brief Summary
The designed study follows up the retrospective previous one by the International T-cell Non-Hodgkin's Lymphoma Study Group (International Peripheral T-Cell Lymphoma Project). It is designed as a pro...
Detailed Description
Peripheral T-cell lymphomas (PTCLs) comprise a heterogeneous group of neoplasms that are derived from post-thymic lymphoid cells at different stages of differentiation with different morphological pat...
Eligibility Criteria
Inclusion
- Previously-untreated patients with de novo diagnosis of peripheral T-cell or NK/T-cell lymphoma:
- Peripheral T-cell lymphoma unspecified;
- Peripheral T-cell lymphoma, lymphoepithelioid variant;
- Peripheral T-cell lymphoma, T-zone variant ;
- Peripheral T-cell lymphoma, parafollicular variant ;
- Angioimmunoblastic T-cell lymphoma;
- Nasal NK/T-cell lymphoma;
- NK/T-cell lymphoma, nasal time;
- Anaplastic large-cell lymphoma, T/null cell, ALK+, primary systemic type
- Anaplastic large-cell lymphoma, T/null cell, ALK-, primary systemic type
- Anaplastic large cell lymphoma, small cell variant, ALK+
- Anaplastic large cell lymphoma, lymphohistiocytic variant, ALK+
- Enteropathy- type T-cell lymphoma;
- Hepatosplenic T-cell lymphoma;
- Peripheral gamma-delta T-cell lymphoma;
- Subcutaneous panniculitis-like T-cell lymphoma;
- Unclassifiable peripheral T-cell Lymphoma
- Unclassifiable NK-cell lymphoma
- Age over 18
- Tissue biopsies adequate for diagnosis and classification and available for centralized review
- Clinical data including baseline information on disease localization and laboratory parameters at staging, features of treatment adopted and assurance of follow-up updating for at least 5 years are requested
- Written informed consent
Exclusion
- Age \< 18
- Diagnosis of T-cell or NK-cell leukemia or proliferation and other than mature types including:
- Adult T-cell leukemia/lymphoma;
- Blastic NK-cell leukemia/lymphoma;
- Aggressive NK-cell leukemia
- T-cell large granular lymphocytic leukemia
- T-cell large granular lymphocytic proliferation
- NK-cell large granular lymphocytic proliferation
- T-cell prolymphocytic leukemia
- Precursor T-cell lymphoblastic leukemia/lymphoma
- Mycosis fungoides;
- Sézary syndrome;
- Primary cutaneous ALCL
Key Trial Info
Start Date :
September 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2018
Estimated Enrollment :
1650 Patients enrolled
Trial Details
Trial ID
NCT01142674
Start Date
September 1 2006
End Date
December 1 2018
Last Update
July 8 2019
Active Locations (76)
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1
Stanford University Medical Center
Palo Alto, California, United States, 94301
2
Yale Cancer Center
New Haven, Connecticut, United States, 06510
3
St Louis Washington University
St Louis, Missouri, United States, 63130
4
University of Nebraska Medical Center
Omaha, Nebraska, United States, 68022