Status:
COMPLETED
Hair Cortisol and Testosterone Levels in Patients With and Without Acute Myocardial Infarction(MI)
Lead Sponsor:
Meir Medical Center
Conditions:
Acute Myocardial Infarction
Eligibility:
MALE
30+ years
Brief Summary
The purpose of this study is to determine whether hair levels of cortisol and testosterone are elevated in patients with acute MI compared to controls.
Detailed Description
Recently there has been a growing interest in measuring hair cortisol and testosterone levels. Hair grows approximately 1 centimeter per month, and hair analysis accurately reflects long-term endogeno...
Eligibility Criteria
Inclusion
- General:
- Males
- Age\>30
- Cases:
- Patients with acute MI ( elevated cardiac enzymes + chest pain or typical ECG changes)
- Control group 1:
- Will include patients with at least 1 of the following:
- Prior cardiovascular disease (CVD). CVD is defined as a history of hospital admission due to acute coronary artery occlusion, percutaneous coronary interventions (PCI), coronary artery bypass grafting, any aortic or peripheral vascular disease that was either symptomatic or required intervention, ischemic or hemorrhagic stroke or transient ischemic attack.
- Diabetes mellitus. (Defined when it is reported by the patient or appears in his medical records, or if the patient has received regular treatment with oral hypoglycemic agents or insulin)
- Control group 2:
- Patients without prior cardiovascular disease or diabetes mellitus (see definitions above).
Exclusion
- Corticosteroid treatment in the last 12 months.
- Diagnosis of Cushing's or Addison's disease.
- Diagnosed hypogonadism treated with testosterone
- Dyed hair.
- Inability to sign inform consent.
- Any hospital admission during the 6 months prior to enrolment
- Morbid obesity (BMI\>35)
Key Trial Info
Start Date :
August 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT01144065
Start Date
August 1 2010
Last Update
May 16 2012
Active Locations (1)
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1
Meir Medical Center
Kfar Saba, Israel, Israel