Status:
COMPLETED
Population Pharmacokinetics of Fentanyl in Patients Undergoing Living Donor Liver Transplantation
Lead Sponsor:
Asan Medical Center
Collaborating Sponsors:
Ministry of Health & Welfare, Korea
Conditions:
Living Donor Liver Transplantation
Eligibility:
All Genders
19-65 years
Phase:
NA
Brief Summary
The aim of this study was to characterize pharmacokinetics of fentanyl during and after Living Donor Liver Transplantation (LDLT), using population pharmacokinetic analysis with non linear mixed effec...
Detailed Description
Patients received an initial intravenous bolus of fentanyl 100 μg and infused at variable rates ranging from 250 to 400 μg/hr. Arterial blood samples (3ml) were taken immediately before the start of ...
Eligibility Criteria
Inclusion
- Patients between 19 - 65 years of age
- Over 45kg of weight
- Written Informed consent
- Patients receiving a liver graft from living donor (ASA PS III or IV)
Exclusion
- Patients with renal dysfunction
- Patients with Fulminant hepatic failure
- Patients participated other clinical trials within 2 months
- Unable or Unwilling to give informed consent
- Abnormal test results with clinical significance
Key Trial Info
Start Date :
September 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2010
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01144312
Start Date
September 1 2009
End Date
October 1 2010
Last Update
June 22 2011
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Asan Medical Center
Seoul, South Korea, 138-736