Status:
COMPLETED
Cephalic Phase Insulin Secretion and Capillary Recruitment in Healthy Men
Lead Sponsor:
Rio de Janeiro State University
Collaborating Sponsors:
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Conditions:
Microvascular Function
Eligibility:
MALE
18-30 years
Phase:
NA
Brief Summary
Forty healthy volunteers will undergo two nailfold-videocapillaroscopy exams with a 10-minute interval between them, after an 10-h overnight fast in a temperature controlled room. The subjects will be...
Eligibility Criteria
Inclusion
- Healthy male volunteers
- Aged between 18 and 30 years
- BMI between 18.5 and 24.9 kg/m2
Exclusion
- Diabetes mellitus, glucose intolerance or altered fasting glucose;
- Hypertension (Systolic pressure ≥ 130 mmHg and diastolic pressure ≥ 80 mmHg);
- HOMA-index ≥ 2.71
- Dyslipidemia
- Renal disease, coronary or peripheral vascular diseases, haematologic or hepatic diseases
- Smoking
- Chronic use of any medication
Key Trial Info
Start Date :
June 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2010
Estimated Enrollment :
39 Patients enrolled
Trial Details
Trial ID
NCT01145027
Start Date
June 1 2009
End Date
August 1 2010
Last Update
October 21 2010
Active Locations (1)
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1
Laboratorio de Pesquisas Clinicas e Experimentais em Biologia Vascular
Rio de Janeiro, Rio de Janeiro, Brazil, 20550-013