Status:
COMPLETED
Fruit And Vegetables and OUtcomes After Removal of Impacted TEeth
Lead Sponsor:
University of Birmingham
Collaborating Sponsors:
NSA, Inc
Conditions:
Postoperative Morbidity
Trauma
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The proposed study will test the following hypotheses: 1. Pre-operative daily dual supplementation with Juice Plus+ (fruit \& vegetable) for 11 weeks will result in reduced post-operative morbidity i...
Detailed Description
In general antioxidant status appears to influence wound healing in humans and in animal models of acute trauma, with low antioxidant concentrations and excessive oxidative stress being associated wit...
Eligibility Criteria
Inclusion
- Patient requiring surgical removal of a single (unilateral) mandibular wisdom tooth
- Tooth requiring full mucoperiosteal flap to be raised for removal
- Bone removal necessary during procedure.
Exclusion
- Patients refusing to give written informed consent
- Clinically significant or unstable physical or mental disability rendering the participants incapable of complying with the study protocol as judged by the investigator
- Pregnant or breast-feeding women
- Patients taking long term anti-microbial or anti-inflammatory drugs
- Patients unable to swallow Juice Plus capsules
- Patients taking regular vitamin or mineral supplementation
- Patients requiring pre-operative antibiotics for surgery
- Patients requiring concomitant extractions or contralateral lower 3rd molar removal
- Allergic to any of the ingredients contained in supplements or placebo medication.
Key Trial Info
Start Date :
June 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2013
Estimated Enrollment :
246 Patients enrolled
Trial Details
Trial ID
NCT01145820
Start Date
June 1 2010
End Date
April 1 2013
Last Update
October 9 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Birmingham
Birmingham, West Midlands, United Kingdom, B18 4DA