Status:

TERMINATED

The Optimal Dosage of Intrathecal Morphine for Peripartum Analgesia

Lead Sponsor:

Beth Israel Deaconess Medical Center

Conditions:

Labor Pain

Eligibility:

FEMALE

18-50 years

Phase:

NA

Brief Summary

The purpose of this study is to determine the ideal dosage of intrathecal morphine for intra and post partum analgesia, while minimizing the side effect profile.

Detailed Description

Regional anesthesia techniques such as combined spinal epidural (CSE) analgesia are very effective for the management of intrapartum pain. The advantages of these techniques are that they are safe whe...

Eligibility Criteria

Inclusion

  • singleton pregnancy,
  • at least 36 weeks gestational age,
  • active labor (≤ 5 cm dilation) requesting neuraxial analgesia,
  • ASA I or II,
  • not currently taking pain medications.

Exclusion

  • multiple gestation,
  • preterm labor,
  • systemic opioids in the past 4 hours,
  • chronic pain syndromes,
  • chronic opioid use,
  • contraindications to regional anesthesia,
  • allergies to opioids,
  • significant co existing medical problems,
  • severe pregnancy induced hypertension,
  • sedatives,
  • magnesium therapy,
  • diabetes type 1.

Key Trial Info

Start Date :

July 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2015

Estimated Enrollment :

83 Patients enrolled

Trial Details

Trial ID

NCT01146457

Start Date

July 1 2010

End Date

January 1 2015

Last Update

April 25 2017

Active Locations (1)

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Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States, 02215