Status:

COMPLETED

Misoprostol Prior to Intrauterine Device (IUD) Insertion in Nulliparous Women

Lead Sponsor:

Emory University

Conditions:

Contraception

Eligibility:

FEMALE

18-45 years

Phase:

NA

Brief Summary

Because of misoprostol's known ability to cause cervical dilation, some family planning providers give their patients a dose of this drug prior to insertion. The goal of this study is to evaluate whet...

Detailed Description

There are currently 2 intrauterine devices (IUDs) available in the U.S., the copper T380 (paragard) and levonorgestrel IUD (Mirena). The effectiveness of IUDs is very similar to tubal sterilization\[1...

Eligibility Criteria

Inclusion

  • 18 years
  • negative pregnancy test
  • no prior pregnancy beyond 19 6/7 weeks
  • no pelvic inflammatory disease in last 3 months
  • no current cervicitis
  • willing to follow up in 1-2 months

Exclusion

  • active cervical infection
  • current pregnancy
  • prior pregnancy beyond 19 6/7 weeks
  • uterine anomaly
  • fibroid uterus distorting uterine cavity
  • copper allergy or wilson's disease for ParaGard
  • undiagnosed abnormal uterine bleeding
  • cervical or uterine cancer
  • sepsis associated with the most recent pregnancy
  • current breast cancer for levonogestrel IUD
  • inflammatory bowel disease
  • allergy to misoprostol

Key Trial Info

Start Date :

June 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2011

Estimated Enrollment :

78 Patients enrolled

Trial Details

Trial ID

NCT01147497

Start Date

June 1 2010

End Date

September 1 2011

Last Update

January 12 2018

Active Locations (1)

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1

The Emory Clinic

Atlanta, Georgia, United States, 30322