Status:

UNKNOWN

Propofol and Remifentanyl Versus Midazolam and Fentanyl for Diagnostic Colonoscopy in Patients With Compensated Cirrhosis Child A-B

Lead Sponsor:

Ziv Hospital

Conditions:

Liver Disease

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

This is a prospective, randomized-controlled trial (RCT) comparing the use of Propofol and Remifentanyl and traditional sedation (Midazolam and Fentanyl) for diagnostic colonoscopies in patients with ...

Eligibility Criteria

Inclusion

  • Consecutive patients older than 18 and younger than 75 years with cirrhosis defined by the presence of liver fibrosis at least F3 and higher in the METAVIR score or with established cirrhosis (Child Pugh A, B)

Exclusion

  • Patients with significant cardiorespiratory disease i.e. advanced respiratory, renal and heart failure (ASA class III or higher except for patients with decompensate liver cirrhosis), obstructive sleep apnea.
  • HCC

Key Trial Info

Start Date :

August 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2012

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT01148277

Start Date

August 1 2011

End Date

February 1 2012

Last Update

April 6 2011

Active Locations (1)

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Ziv medical center liver unit

Safed, Israel, Israel, 13100