Status:
COMPLETED
Effect of Olanzapine on Sleep Electroencephalogram (EEG) in Schizophrenia Patients
Lead Sponsor:
Central Institute of Psychiatry, Ranchi, India
Conditions:
Schizophrenia
Sleep
Eligibility:
MALE
18-45 years
Phase:
PHASE4
Brief Summary
Acute and sub-chronic administration of olanzapine has shown a favourable effect on the sleep disturbances in previously medicated schizophrenia patients with predominantly negative symptoms. The pres...
Detailed Description
Twenty schizophrenia patients (11 drug naïve and 9 drug free) will be studied over a period of six weeks of olanzapine treatment. Patients will be assessed at the baseline on BPRS, PANSS, CDSS and UKU...
Eligibility Criteria
Inclusion
- Male patients fulfilling International Classification of Diseases-10 Diagnostic Criteria for Research for schizophrenia
- Aged 18-50 Yrs
- Drug naïve or drug free (not receiving any psychotropic medication for the past 4 months)
- Consenting
Exclusion
- Any comorbid psychiatric illness
- Significant medical or neurological illness
- History of significant head injury, epilepsy
- Substance use in the past 4 months excluding nicotine and caffeine
- Presence of a primary sleep disorder
Key Trial Info
Start Date :
August 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2009
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT01149577
Start Date
August 1 2007
End Date
April 1 2009
Last Update
June 23 2010
Active Locations (1)
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1
Central Institute of Psychiatry
Ranchi, Jharkhand, India, 834006