Status:

COMPLETED

Neuromodulation in Depressed and Schizophrenic Patients - Changing MEP (Muscle Evoked Potentials) by tDCS (Transcranial Direct Current Stimulation)

Lead Sponsor:

Ludwig-Maximilians - University of Munich

Conditions:

Schizophrenia

Depression

Eligibility:

All Genders

18-65 years

Brief Summary

Muscle evoked potentials (MEP) are supposed to different in schizophrenic and depressed patients, compared to a sample of healthy volunteers. Transcranial Magnetic Stimulation (TMS)-evoked MEP are mea...

Eligibility Criteria

Inclusion

  • The patient must be in the condition to understand the patient-information, as well as the necessary examinations.
  • He/she must be able to give a written consent.
  • No medication at least three weeks before enrollment.

Exclusion

  • Existence of a care/legal incapacity
  • Existing pregnancy
  • Severe psychiatric illness (with exception of affective disorder)
  • Acute suicidality
  • Drug-, medication- or alcohol dependence
  • Dementia according to DSM IV / ICD 10-criterions
  • Severe brain infarctus in the anamnesis
  • Indications of structural damage of the basal ganglia or the brain stem
  • Severe neurological disorders (e.g. M. Parkinson, epilepsy, discus-prolapse, dementia, systemic neurological illnesses, normal pressure hydrocephalus, cerebrovascular diseases, elevated intracranial pressure, in the last 6 months, polyneuropathies).
  • Severe other medical conditions, like manifest arterial hypertonia, severe heart disease, pacemakers, respiratory failure, malignant illnesses all type, also in the history, active infectious diseases, skeletal disorders (like M. Paget, osteoporosis with spontaneous fractures, fresh fractures) Other circumstances, that speaks against a participation of the patient pinion of Medical Doctor at this study.

Key Trial Info

Start Date :

October 1 2009

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2011

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT01150734

Start Date

October 1 2009

End Date

January 1 2011

Last Update

April 22 2011

Active Locations (1)

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Ludwig-Maximilians-University

Munich, Germany, 80333