Status:

UNKNOWN

Safety and Efficacy of Autologous Bone Marrow Stem Cells for Treating Osteoarthritis

Lead Sponsor:

International Stemcell Services Limited

Conditions:

Osteoarthritis

Eligibility:

All Genders

30-70 years

Phase:

PHASE1

PHASE2

Brief Summary

Osteoarthritis is a leading cause of chronic disability in elderly and the risk of disability attributed to osteoarthritis is as great as or greater than due to any other medical condition in that age...

Eligibility Criteria

Inclusion

  • Must be able to give voluntary written (patients may not be able to write) consent.
  • Must be able to understand study information provided to him.
  • Age 30 to 70, inclusive
  • OA Kellgren and Lawrence classification 3 \& 4
  • No ligamentous laxity i.e. stable
  • Ability to understand and willingness to sign consent form
  • The participant is able to comply with and understand the required visit schedule and all required tests and procedures.

Exclusion

  • Serious pre-existing medical conditions like Diabetes Mellitus, Chronic Renal Failure, Rheumatoid Arthritis, Collagen vascular diseases and Autoimmune diseases
  • Pregnant or lactating woman
  • Inflammatory arthritis
  • Oral steroid, methotrexate (immune suppressants)
  • History of drug or alcohol abuse or chronic smoking
  • Poor patient compliance
  • Infectious disease test positive for HIV 1\&2, HbsAg, HCV and VDRL.

Key Trial Info

Start Date :

January 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2012

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT01152125

Start Date

January 1 2010

End Date

January 1 2012

Last Update

June 9 2011

Active Locations (1)

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1

St. Theresa's Hospital

Bengaluru, Karnataka, India, 560010