Status:

COMPLETED

Study to Evaluate Safety and Immunogenicity of Sub-unit Adjuvanted Influenza Vaccine Administered to Elderly Subjects, Formulation 2010-2011

Lead Sponsor:

Novartis Vaccines

Conditions:

Seasonal Influenza

Eligibility:

All Genders

65+ years

Phase:

PHASE2

Brief Summary

This study will evaluate the safety and immunogenicity of a sub-unit, adjuvanted influenza vaccine administered to elderly subjects

Eligibility Criteria

Inclusion

  • Key
  • Males and females volunteers of 65 years of age or older
  • Mentally competent
  • Willing and able to give written informed consent prior to study entry.
  • Able to comply with all the study requirements.
  • In general good health
  • Key

Exclusion

  • Any serious chronic or acute disease
  • History of any anaphylactic reaction and/or serious allergic reaction following a vaccination
  • Known or suspected impairment/alteration of immune function
  • Bleeding diathesis or conditions associated with prolonged bleeding time that in the investigator's opinion would interfere with the safety of the subject
  • Within the past 6 months, they have had laboratory confirmed influenza disease or received influenza vaccine
  • Fever (i.e., axillary temperature ≥38°C) within the last 3 days of intended study vaccination
  • Individuals who received any other vaccines within 4 weeks prior to enrollment in this study or who are planning to receive any vaccine within 4 weeks from the study vaccines

Key Trial Info

Start Date :

June 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2010

Estimated Enrollment :

64 Patients enrolled

Trial Details

Trial ID

NCT01152814

Start Date

June 1 2010

End Date

July 1 2010

Last Update

January 27 2016

Active Locations (6)

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Page 1 of 2 (6 locations)

1

Dipartimento di Medicina e Scienze dell'Invecchiamento, Università G. D'Annunzio, Via dei Vestini

Chieti, Italy, 66100

2

Dipartimento di Medicina Clinica e Sperimentale - Sezione di Igiene e Medicina Preventiva, Via Fossato di Mortara, 64/b

Ferrara, Italy, 44100

3

Dipartimento di Scienze della Salute Università di Genova Via Pastore, 1

Genova, Italy, 16132

4

Centro Satellite. ASL Lanciano - Vasto, sede legale Via S. Spaventa, 37

Lanciano, Italy, 66034