Status:
COMPLETED
Periodontal Disease and Circulatory Microbial Components
Lead Sponsor:
University of Michigan
Conditions:
Periodontal Disease
Eligibility:
All Genders
35+ years
Brief Summary
The goal of this project is to study the immune activity of certain proteins present in the blood of patients with severe periodontal disease. Periodontal disease (gum disease) is the major cause of t...
Detailed Description
This project will have two specific goals: 1. Identify microorganism components in the serum of patients with severe periodontitis; and 2. Characterize the immune regulator activity of periodontitis s...
Eligibility Criteria
Inclusion
- 35 years or older
- Healthy patients or patients with severe periodontal disease
- Patients with or without Rheumatoid Arthritis
- Patients with at least 20 permanent teeth
Exclusion
- Patients undergoing long-term (over 2 weeks) antibiotic-related therapy 3 months prior to study inclusion
- Patients receiving periodontal treatment 12 months prior to study inclusion (INCLUDING CLEANINGS)
- Patients will be excluded if they receive long-term use of medications known to affect periodontal status such as anti-inflammatory drugs, aspirin and ibuprofen
- Patients on immunosuppressive therapies, including glucocorticoids or cyclosporines, are excluded from participation in this study (inhalers are allowed)
- History of metabolic bone diseases such as rheumatoid arthritis or post-menopausal osteoporosis
- Pregnant women or women attempting to become pregnant
Key Trial Info
Start Date :
January 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2015
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT01154855
Start Date
January 1 2010
End Date
May 1 2015
Last Update
December 14 2015
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.