Status:
TERMINATED
Aspirin and Plavix Following Coronary Artery Bypass Grafting
Lead Sponsor:
Ahmad Slim
Collaborating Sponsors:
Bristol-Myers Squibb
Conditions:
Coronary Graft Patency
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The design of the study will be randomized, double blind trial, which will examine the effects of addition of clopidogrel to current guideline recommended background therapy on lowering the incidence ...
Detailed Description
The purpose of this study is to evaluate how well the combination of clopidogrel and aspirin lower the risk of clot forming in the bypass graft after open heart surgery. This combination has not yet b...
Eligibility Criteria
Inclusion
- Patients undergoing coronary artery bypass grafting, with or without cardiopulmonary bypass
- Age ≥ 18
Exclusion
- Left ventricle ejection fraction \<30%
- Emergency surgery
- Valve surgery
- Redo CABG
- Postoperative cardiogenic shock for more than 48 hours
- Postoperative bleeding or cardiac tamponade
- More than 24 hours postoperative intubation course
- Requirement of postoperative anticoagulation
- Serum creatinine \>1.4
- Contraindication to use of postoperative coronary CT scan
- Allergy or contraindication to aspirin or clopidogrel
- Inability to provide informed consent
- Pregnant or breast feeding females
Key Trial Info
Start Date :
July 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2014
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01158703
Start Date
July 1 2010
End Date
December 1 2014
Last Update
May 19 2015
Active Locations (1)
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1
Brooke Army Medical Center
San Antonio, Texas, United States, 78234