Status:
COMPLETED
Live Kidney Donor Study -Renal Function Study
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Health Resources and Services Administration (HRSA)
Conditions:
Kidney Donation
Kidney Failure
Eligibility:
All Genders
Brief Summary
Kidney transplantation from living donors has been shown to carry many benefits over deceased donor transplantation. Because of benefits such as shorter waiting times and improved outcome for transpla...
Detailed Description
Previous studies poorly describe renal function after kidney donation. Most published studies of renal function after donation are based on predictive equations, which were not designed for living kid...
Eligibility Criteria
Inclusion
- Underwent unilateral donor nephrectomy between 5 and 50 years ago; but no later than June 30, 2005 at Mayo Clinic or University of Minnesota
- Alive at the time of study recruitment
- Underwent GFR measurement before and early after donor nephrectomy (Mayo Clinic participants only)
- Underwent GFR measurement late after donor nephrectomy and 3 or more years prior to the invitation to participate in this study (UMN participants only)
- Self reported black race (UAB participants only)
- Negative serum pregnancy test (Total Beta Human Chorionic Gonadotropin (HCG) \<5) for women of child-bearing potential
Exclusion
- Less than 5 years out from time of kidney donation
- Inability to contact donor
- Inability or unwillingness to provide informed consent
- Iodine or iodinated contrast allergy.
- Pregnant or breast feeding women
Key Trial Info
Start Date :
September 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2012
Estimated Enrollment :
402 Patients enrolled
Trial Details
Trial ID
NCT01158742
Start Date
September 1 2009
End Date
June 1 2012
Last Update
March 27 2017
Active Locations (3)
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1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
2
University of Minnesota
Minneapolis, Minnesota, United States, 55455
3
Mayo Clinic
Rochester, Minnesota, United States, 55905