Status:

COMPLETED

Incidence of Occluded Culprit Arteries and Impact of Coronary Collaterals on Outcome in Patients With NSTEMI

Lead Sponsor:

University of Jena

Conditions:

NSTEMI

Eligibility:

All Genders

18-90 years

Phase:

PHASE4

Brief Summary

It is assumed that patients with non-ST-elevation myocardial infarctions (NSTEMI) showing an infero- or posterolateral occluded culprit artery (OCA) during diagnostic angiography frequently elude stan...

Detailed Description

We examined consecutive NSTEMI patients within 48 h of symptom onset. All patients underwent early invasive angiography plus optimal medical therapy. We compared baseline characteristics, procedural f...

Eligibility Criteria

Inclusion

  • age between 18 and 90 years,
  • onset of angina pectoris at rest \<24 h or crescendo angina in recent weeks with symptoms under minimal exertion or at rest lasting \<24 h,
  • elevated troponin T ≥0.03 µg/L and
  • written informed consent.

Exclusion

  • persistent angina,
  • ST-segment elevation myocardial infarction (STEMI),
  • hemodynamic instability including cardiogenic shock,
  • oral anticoagulation therapy,
  • contraindications for glycoprotein IIb/IIIa inhibitors,
  • other disease with life expectancy \<6 months,
  • known coagulopathy,
  • pregnancy,
  • other suspected causes of troponin elevation as myocarditis, secondary to hypertensive crisis, or after cardiac decompensation,
  • no ability to consent, and
  • participation in another study.

Key Trial Info

Start Date :

July 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2010

Estimated Enrollment :

602 Patients enrolled

Trial Details

Trial ID

NCT01159366

Start Date

July 1 2006

End Date

January 1 2010

Last Update

July 12 2010

Active Locations (1)

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1

University of Leipzig

Leipzig, Germany, 04289