Status:

COMPLETED

2D Strain Echocardiography for Diagnosing Chest Pain in the Emergency Room

Lead Sponsor:

Technion, Israel Institute of Technology

Conditions:

Chest Pain

Coronary Artery Disease

Eligibility:

All Genders

45+ years

Brief Summary

Background: Chest pain (CP) and suspected heart attack is the second most frequent complaint among patients presenting to the emergency department (ED). Present workup involves in-hospital observation...

Eligibility Criteria

Inclusion

  • Patients presenting to the emergency department with chest pain characteristic for ischemia and suspected acute coronary syndrome and at least one of the following:
  • Planned emergency department or chest pain unit observation for at least 6 hours
  • Hospital or chest pain unit admission for suspected acute coronary syndrome
  • Planned coronary CT scan
  • Age ≥ 45 years old
  • Normal sinus rhythm
  • Patient able to give an informed consent

Exclusion

  • ST elevation MI (≥ 1mm in at least 2 contiguous leads) or unstable patients requiring urgent care
  • Significant (≥ 1mm ST depression in at least 2 contiguous leads) on initial ECG
  • Elevated troponin on first examination
  • History of previous MI, CABG, significant Q waves on ECG or wall motion abnormality on a previous echo
  • Atrial fibrillation or abundant arrhythmia
  • CLBBB, Ventricular pacing
  • Valvular disease of at least moderate severity
  • Cardiomyopathy
  • Abnormal septal motion due to right ventricular disease or lung disease
  • Technically suboptimal echo study (\> 2 segments of suboptimal quality from apical views)
  • Pregnancy
  • Inadequate strain tracing

Key Trial Info

Start Date :

September 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 1 2014

Estimated Enrollment :

700 Patients enrolled

Trial Details

Trial ID

NCT01163019

Start Date

September 1 2010

End Date

September 1 2014

Last Update

October 28 2014

Active Locations (11)

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Page 1 of 3 (11 locations)

1

Ha'Emek Medical Center,

Afula, Israel

2

Soroka University Medical Center

Beersheba, Israel

3

Hillel Yafe Medical Center

Hadera, Israel

4

Lady Davis Carmel Medical Center

Haifa, Israel