Status:
COMPLETED
Effects of Tofacitinib (CP-690,550) on Magnetic Resonance Imaging (MRI)- Assessed Joint Structure In Early Rheumatoid Arthritis (RA)
Lead Sponsor:
Pfizer
Conditions:
Rheumatoid Arthritis
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Evaluation of efficacy and safety of tofacitinib (CP-690,550) for the treatment of early rheumatoid arthritis in adult patients with moderate to severe disease who are methotrexate naïve. The efficacy...
Eligibility Criteria
Inclusion
- Adult patients with moderate to severe early rheumatoid arthritis (\< 2 years) who are methotrexate and biologic disease modifying antirheumatic drug naive.
Exclusion
- Pregnant or lactating patients;
- Patients with renal or hepatic impairment or other severe or progressing disease;
- Patients with contraindication to magnetic resonance imaging with gadolinium contrast.
Key Trial Info
Start Date :
October 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2013
Estimated Enrollment :
109 Patients enrolled
Trial Details
Trial ID
NCT01164579
Start Date
October 1 2010
End Date
November 1 2013
Last Update
April 22 2015
Active Locations (40)
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1
ArthroCare, Arthritis Care & Research, PC
Gilbert, Arizona, United States, 85234
2
Talbert Medical Group
Huntington Beach, California, United States, 92646
3
Inland Rheumatology Clinical Trials, Inc.
Upland, California, United States, 91786
4
Millennium Research
Ormond Beach, Florida, United States, 32174