Status:

COMPLETED

Safety and Efficacy Study Comparing 3 New Types of Coronary Stents

Lead Sponsor:

University Hospital, Basel, Switzerland

Conditions:

Coronary Artery Disease

Coronary Thrombosis

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Background: Retrospective analyses of long-term BASKET findings identified patients with large drug-eluting stents (DES) (\>2.5mm Stents) as patients at risk for late cardiac death/nonfatal myocardia...

Detailed Description

Background and Study Design The study is a multicentre, prospective, randomized, open-label trial comparing safety and efficacy of the Nobori® drug-eluting stent (DES), the Xience Prime® DES, and the...

Eligibility Criteria

Inclusion

  • written informed concent
  • need for large (≥3.0 mm stents only) native vessel stenting

Exclusion

  • in-Stent Restenosis or in-Stent Thrombosis
  • bypass graft disease to be stented
  • main stem disease to be stented
  • cardiogenic shock by clinical assessment (signs of organ hypoperfusion)
  • planned surgery within the next 12 months
  • oral anticoagulation needed (artificial heart valves,atrial fibrillation) or chronic haemorrhagic diathesis
  • active bleeding disorders
  • index-PCI = planned PCI of additional lesion
  • no follow-up (FU) expected/possible
  • History of stroke or TIA (contraindication for prasugrel)
  • known severe hypersensitivity reaction to ASS and/or Prasugrel
  • no compliance expected / no informed consent given
  • enrolled in another study

Key Trial Info

Start Date :

April 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2014

Estimated Enrollment :

2291 Patients enrolled

Trial Details

Trial ID

NCT01166685

Start Date

April 1 2010

End Date

May 1 2014

Last Update

June 5 2014

Active Locations (8)

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Page 1 of 2 (8 locations)

1

Universitätsklinikum

Innsbruck, Austria, 6020

2

Gentofte Hospital

Hellerup, Denmark, 2900

3

Elisabethen Krankenhaus

Essen, North Rhine-Westphalia, Germany, 45138

4

Kantonsspital

Aarau, Canton of Aargau, Switzerland, 5000