Status:
TERMINATED
Carbon Ion Radiotherapy for Hepatocellular Carcinoma
Lead Sponsor:
University Hospital Heidelberg
Conditions:
Hepatocellular Carcinoma
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Treatment options for patients with advanced hepatocellular carcinoma (HCC) are often limited. In most cases, they are not amenable to local therapies including surgery or radiofrequency ablation. The...
Eligibility Criteria
Inclusion
- histologically confirmed HCC or diagnosis of HCC according to AASLD-guidelines
- macroscopic tumor
- liver-confined disease without extrahepatic disease as diagnosed by CT, MRT, ultrasound and bone scan
- minimal distance of tumor edge to the intestines of 1cm
- age ≥ 18 years of age
- Karnofsky Performance Score ³60
- For women with childbearing potential, (and men) adequate contraception.
- Ability of subject to understand character and individual consequences of the clinical trial
- Written informed consent (must be available before enrolment in the trial)
Exclusion
- refusal of the patients to take part in the study
- previous radiotherapy of the hepatobiliary system
- margin of \< 1cm between tumor edge and intestines
- Patients who have not yet recovered from acute toxicities of prior therapies
- Known carcinoma \< 2 years ago (excluding Carcinoma in situ of the cervix, basal cell carcinoma, squamous cell carcinoma of the skin) requiring immediate treatment interfering with study therapy
- Pregnant or lactating women
- Participation in another clinical study or observation period of competing trials, respectively
Key Trial Info
Start Date :
August 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2022
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT01167374
Start Date
August 1 2011
End Date
August 1 2022
Last Update
November 3 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital of Heidelberg, Radiation Oncology
Heidelberg, Germany, 69120