Status:
WITHDRAWN
Exclusive Hypofractionated Stereotactic Radiotherapy in Non-resectable Single Brain Metastasis
Lead Sponsor:
Barretos Cancer Hospital
Conditions:
Cancer
Metastasis
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
Patients with single brain metastasis without other metastatic site have a better prognosis, and they need a better brain metastasis control. For non-resectable and non-radiosurgical brain metastasis,...
Detailed Description
For the planning, patients will undergo magnetic resonance imaging (MRI) 1.5 to 3 Tesla, with contrast and volumetric reconstruction of 1 mm and can be used MRI from the diagnosis of metastasis, if it...
Eligibility Criteria
Inclusion
- Histopathology of primary tumors: all but the primary characteristics of melanoma cancer, small cell lung cancer, germ cell tumors, leukemia or lymphoma, or primary central nervous system.
- Primary-site: controlled, meaning operated and / or irradiated tumor activity without detectable local
- Meningeal dissemination: none
- Extra-cranial metastases: none
- Pre-irradiation brain: absent
- Number of brain metastases: one
- Location of brain metastasis: brain regions not eligible for surgery (such as the hippocampus, amygdala, motor area, eloquent cortex, thalamus, hypothalamus, basal ganglia, optic tract, midbrain, pons, medulla, corpus callosum and internal capsule) or radiosurgery( metastasis \<5 mm from the thalamus, hypothalamus, basal ganglia, optic tract, midbrain, pons, medulla, corpus callosum and internal capsule, and / or ≥ 10 ml or ≥ 3 cm in greatest diameter, or 10 ml tissue receiving ≥ 12 Gy).
- Karnofsky Performance Status ≥ 70%
- Informed consent: authorized
Exclusion
- patients that don't have the eligibility below
Key Trial Info
Start Date :
July 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01169116
Start Date
July 1 2010
Last Update
February 4 2014
Active Locations (1)
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1
Barretos Cancer Hospital
Barretos, São Paulo, Brazil, 14784-400