Status:

COMPLETED

Biomarkers in Bone Marrow and Blood Samples From Older Patients With Acute Myeloid Leukemia Treated With Cytarabine-Based Therapy

Lead Sponsor:

ECOG-ACRIN Cancer Research Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Leukemia

Eligibility:

All Genders

60-120 years

Brief Summary

RATIONALE: Studying samples of bone marrow and blood from patients with cancer in the laboratory may help doctors predict how well patients will respond to treatment. PURPOSE: This research study is ...

Detailed Description

OBJECTIVES: Primary * To validate a pre-specified proteomic classifier to predict the likelihood of complete response (CR) to cytarabine-based induction chemotherapy in older patients with non-M3 ac...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Treated on EST-1490, E-3993, or ECOG-E3999
  • Bone marrow and peripheral blood samples collected at diagnosis and before induction chemotherapy available
  • No M3 disease
  • PATIENT CHARACTERISTICS:
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • See Disease Characteristics

Exclusion

    Key Trial Info

    Start Date :

    July 8 2010

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    August 8 2010

    Estimated Enrollment :

    200 Patients enrolled

    Trial Details

    Trial ID

    NCT01169363

    Start Date

    July 8 2010

    End Date

    August 8 2010

    Last Update

    May 17 2017

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