Status:

COMPLETED

Prophylactic Effects of Ondansetron, Ramosetron, and Palonosetron on Patient-Controlled Analgesia Related Nausea and Vomiting After Urologic Laparoscopic Surgery

Lead Sponsor:

Yonsei University

Conditions:

Laparoscopic Marsupialization of Renal Cyst

Eligibility:

FEMALE

20-65 years

Phase:

NA

Brief Summary

The aim of this prospective randomized controlled study was to compare the prophylactic effects of intravenous single dose of ondansetron, ramosetron, and palonosetron on PCA-related nausea and vomiti...

Eligibility Criteria

Inclusion

  • ASA I or II
  • Patients aged (20-65 yr) Undergoing Laparoscopic Nephrectomy
  • Patients who want a patient-controlled IV analgesia (IV-PCA)

Exclusion

  • History of allergy or hypersensitivity to 5-HT3 antagonist
  • History of severe postoperative nausea/vomiting
  • Prolonged QT interval on preoperative EKG
  • Hypokalemia, Hypomagnesemia
  • Intestinal obstruction
  • Pregnant female or breast feeding mother

Key Trial Info

Start Date :

August 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2011

Estimated Enrollment :

105 Patients enrolled

Trial Details

Trial ID

NCT01169805

Start Date

August 1 2010

End Date

June 1 2011

Last Update

November 18 2011

Active Locations (1)

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1

Severance Hospital, Yonsei University College of Medicine

Seoul, South Korea, 120-752