Status:
UNKNOWN
Efficacy and Safety Study of Procaterol Hydrochloride to Treat Patients With Cough Variant Asthma (CVA)
Lead Sponsor:
Shanghai Jiao Tong University School of Medicine
Conditions:
Cough Variant Asthma
Eligibility:
All Genders
18-75 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to investigate the efficacy and safety of procaterol hydrochloride with inhaled glucocorticoid in treatment patients with cough variant asthma (CVA).
Detailed Description
This is a 8-week, double-blind, randomized, placebo-controlled study, the patients with CVA will be randomized to experimental or placebo control group. During the screening period, eligible patients...
Eligibility Criteria
Inclusion
- male or female patients,18-75 years old;
- cough lasting over 3 weeks ; dry cough or with slight white mucous phlegm; cough is the main clinical symptom or the only symptom;
- without wheeze and fever;
- without the history of upper respiratory tract infection within recent two months; non-smoking or giving-up smoking for over two years;
- without rales from lung;
- no obvious abnormalities from chest X-ray;
- bronchial provocation test: positive.
Exclusion
- patients with chronic pulmonary disease;
- patients who are allergic to ß2 receptor agonist;
- patients taking ß2 receptor agonist for long time;
- severe heart, renal and hepatic disease;
- unable to comply with the protocol;
- pregnant, breast feeding, and childbearing potential women;
- patients improper to the trial according to the investigators' judgment.
Key Trial Info
Start Date :
July 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2011
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT01170429
Start Date
July 1 2010
End Date
February 1 2011
Last Update
July 27 2010
Active Locations (1)
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1
Xin Zhou
Shanghai, Shanghai Municipality, China, 200080