Status:

COMPLETED

Miralax (PEG 3350) vs. Golytely as Bowel Preparation for Screening Colonoscopy

Lead Sponsor:

Temple University

Conditions:

Colon Cancer

Eligibility:

All Genders

40-75 years

Phase:

PHASE4

Brief Summary

A major limitation to the widespread acceptance of colonoscopy as a procedure to screen for colorectal cancer is the laxative preparation. Phosphate-based preps (e.g. Fleets Phosphosoda) are now used ...

Detailed Description

Objective To determine whether Miralax is as efficacious for bowel cleansing as standard Golytely for screening colonoscopy. This study is designed and powered to be an non-inferiority study. Primary...

Eligibility Criteria

Inclusion

  • All adults undergoing average risk colon cancer screening (ages 40-75 years old)
  • •Able to provide informed consent

Exclusion

  • A history of constipation
  • Patients who use medications to assist with a bowel movement such as osmotic, stimulant, or cathartic laxatives (including "colon cleansers")
  • Diabetes or glucose intolerance
  • Patients with severe underlying renal or hepatic impairment
  • Pregnant women - pregnancy test performed on all menstruating women before procedure.

Key Trial Info

Start Date :

April 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2011

Estimated Enrollment :

136 Patients enrolled

Trial Details

Trial ID

NCT01170754

Start Date

April 1 2010

End Date

July 1 2011

Last Update

September 13 2017

Active Locations (1)

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Temple University Hospital

Philadelphia, Pennsylvania, United States, 19140