Status:

COMPLETED

Phamacological Reversal of Airway Instability During Sedation

Lead Sponsor:

University of Rochester

Conditions:

Upper Airway Obstruction

Eligibility:

MALE

18-45 years

Phase:

NA

Brief Summary

The investigators are attempting to demonstrate a decrease in the frequency and severity of sedation-induced respiratory arrhythmias(central and obstructive apneas) with pharmacological pre-treatment ...

Detailed Description

One of the most serious side effects of drugs administered for sedation is untoward respiratory events. The relative prevalence of such events is thought to be high, occurring in up to 41% of patients...

Eligibility Criteria

Inclusion

  • Ages 18-45
  • BMI below 25
  • Healthy males

Exclusion

  • Psychiatric illness
  • Substance abuse
  • Airway disorders
  • Bleeding abnormatlities
  • Claustrophobia
  • Sleep apnea.

Key Trial Info

Start Date :

August 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2011

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT01171118

Start Date

August 1 2009

End Date

August 1 2011

Last Update

April 27 2015

Active Locations (1)

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1

University of Rochester Medical Center

Rochester, New York, United States, 14642