Status:

COMPLETED

Left Atrial Distensibility to Predict Left Ventricular Filling Pressure and Prognosis in Patients With Severe Mitral Regurgitation

Lead Sponsor:

Kaohsiung Veterans General Hospital.

Collaborating Sponsors:

National Science and Technology Council, Taiwan

Conditions:

Mitral Valve Insufficiency

Atrial Fibrillation

Eligibility:

All Genders

Brief Summary

A large left atrial (LA) volume, which represents chronic diastolic dysfunction, is associated with a poor outcome, regardless of systolic function. Thus, the LA volume provides a long-term view of wh...

Detailed Description

Introduction LA volume provides the significantly prognostic information in the general population and patients with heart disease, including acute myocardial infarction, left ventricular dysfunction,...

Eligibility Criteria

Inclusion

  • Patients with severe mitral regurgitation are admitted for surgical intervention and are willing to participate in this study.

Exclusion

  • Presence of mitral stenosis
  • More than mild severity of aortic valvular problem
  • Any abnormality of atrial septum (e.g., atrial septal defect or aneurysm)
  • Rhythm other than sinus rhythm
  • Inadequate image quality
  • Lack of informed consent

Key Trial Info

Start Date :

July 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2011

Estimated Enrollment :

111 Patients enrolled

Trial Details

Trial ID

NCT01172184

Start Date

July 1 2010

End Date

January 1 2011

Last Update

June 7 2011

Active Locations (1)

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Kaohsiung Veterans General Hospital

Kaohsiung, Taiwan, Taiwan, 886