Status:
COMPLETED
Rapid Infusion of Cold Normal Saline During CPR for Patients With Out-of-hospital Cardiac Arrest
Lead Sponsor:
Ambulance Victoria
Collaborating Sponsors:
Western Australian Ambulance Service
South Australian Ambulance Service
Conditions:
Out-of-hospital Cardiac Arrest
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
That paramedic core cooling during CPR using a rapid infusion of ice-cold (4 degrees C) large-volume (30mL/kg) normal saline improves outcome at hospital discharge compared with standard care in patie...
Detailed Description
INTRODUCTION: Pre-hospital cardiac arrest is common and associated with a poor prognosis and only about 8% of patients have a good outcome. For patients who are initially successfully resuscitated by...
Eligibility Criteria
Inclusion
- Patients in cardiac arrest on arrival of paramedics and who:
- Are adults \> 18 years/ are in cardiac arrest (pulseless) on arrival of paramedics
Exclusion
- Patients who are:
- In cardiac arrest following trauma or suspected intra-cranial bleeding/ obviously pregnant/ Dependant on others for activities of daily living (ie any assistance with activities of daily living, in supported care or nursing home residents) or have pre-existing significant neurological injury,Likely to be "Not for Resuscitation" and/or admission to the Intensive Care Unit because of terminal disease or advanced age, Patients who are hypothermic already and are confirmed to be on temperature measurement/ in-hospital cardiac arrest.
Key Trial Info
Start Date :
July 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2014
Estimated Enrollment :
1220 Patients enrolled
Trial Details
Trial ID
NCT01173393
Start Date
July 1 2010
End Date
December 1 2014
Last Update
January 22 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Ambulance Victoria
Melbourne, Australia