Status:

COMPLETED

Open Label, Safety, Tolerability and Efficacy of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias

Lead Sponsor:

Novartis Pharmaceuticals

Conditions:

Parkinson Disease

Dyskinesia, Drug-Induced

Eligibility:

All Genders

Phase:

PHASE2

Brief Summary

The purpose of this study is to generate long-term safety, tolerability and efficacy data for AFQ056 in patients who have participated in and completed any AFQ056 phase II study in PD-LID (Parkinson's...

Eligibility Criteria

Inclusion

  • Outpatients with Parkinson's disease (PD), treated with L-Dopa, experiencing dyskinesias who have been eligible for, participated in and completed an AFQ056 phase II core study.

Exclusion

  • Surgical treatment for PD
  • Cancer within the past 5 years (other than localized skin cancer and prostate cancer that has been effectively treated)
  • Advanced, severe or unstable disease (other than PD) that may interfere with the study outcome evaluations
  • Other protocol-defined inclusion/exclusion criteria may apply

Key Trial Info

Start Date :

October 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2013

Estimated Enrollment :

66 Patients enrolled

Trial Details

Trial ID

NCT01173731

Start Date

October 1 2010

End Date

October 1 2013

Last Update

December 23 2020

Active Locations (22)

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Page 1 of 6 (22 locations)

1

Novartis Investigative Site

Sunnyvale, California, United States, 94089

2

Novartis Investigative Site

Englewood, Colorado, United States, 80113

3

Novartis Investigative Site

Indianapolis, Indiana, United States, 46202

4

Novartis Investigative Site

Heidelberg, Victoria, Australia, 3081