Status:
ACTIVE_NOT_RECRUITING
Growing Up in Singapore Towards Healthy Outcomes
Lead Sponsor:
National University Hospital, Singapore
Collaborating Sponsors:
KK Women's and Children's Hospital
Institute for Human Development and Potential (IHDP), Singapore
Conditions:
Metabolic Diseases
Neurological and Mental Health Conditions
Eligibility:
All Genders
Brief Summary
This study aims to examine the role of genetic and epigenetic factors, maternal nutrition, lifestyle, emotional health, and other environmental factors in pregnancy or postpartum period that can influ...
Detailed Description
The dramatic emergence of non-communicable diseases (NCDs) in Asia has coincided with the rapid socioeconomic and nutritional transition taking place in the region, with the prevalence of diabetes ris...
Eligibility Criteria
Inclusion
- Inclusion Criteria of Mother Participants:
- Women 18 years and above
- Pregnant women attending the first visit (\< 14 weeks GA) at the maternity units of KKH and NUH
- Singapore citizens or Singapore Permanent Residents
- Currently resident in mainland Singapore
- Intention to eventually deliver in KKH or NUH
- Intention to reside in Singapore for the next 5 years
- Intention to donate cord, cord blood and placenta
- The fetus should be racially homogenous with both sets of grandparents of the same ethnicity
- Exclusion Criteria of Mother Participants:
- Women whose pregnancies end in miscarriages will be excluded
- Pregnant women on chemotherapy
- Exclude women with significant medical conditions e.g. Type 1 diabetes mellitus, psychosis etc.
- Exclude women on certain medications - e.g. psychotropic drugs.
- Mixed marriages will be excluded
- Babies born from these mothers will be invited to participate and followed up until the child is at least 20 years of age.
Exclusion
Key Trial Info
Start Date :
June 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2029
Estimated Enrollment :
1247 Patients enrolled
Trial Details
Trial ID
NCT01174875
Start Date
June 1 2009
End Date
July 1 2029
Last Update
April 24 2025
Active Locations (1)
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1
National University Hospital
Singapore, Singapore, Singapore