Status:
COMPLETED
Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents
Lead Sponsor:
University of South Florida
Collaborating Sponsors:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
University of California, Los Angeles
Conditions:
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Eligibility:
All Genders
11-14 years
Phase:
PHASE1
PHASE2
Brief Summary
Comorbid anxiety disorders affect as many as 80% of youth with autism spectrum disorders, causing substantial distress and impairment over and above the autism spectrum diagnosis alone. Cognitive beha...
Detailed Description
Autism spectrum disorders (ASD) affect approximately 1 out of 150 children and adolescents in the United States, making them one of the most common neurobiological conditions. Comorbid anxiety disorde...
Eligibility Criteria
Inclusion
- Outpatient adolescents with ASD (see below) between the ages 11-14 years.
- Meets criteria for a diagnosis of autism, Asperger syndrome (AS), or Pervasive Developmental Disorder Not Otherwise Specified .
- Meets criteria for a diagnosis of one of the following anxiety disorders: separation anxiety disorder (SAD), generalized anxiety disorder (GAD), social phobia, or obsessive compulsive disorder (OCD).
- Child has a Full Scale and Verbal Comprehension IQ≥85.
Exclusion
- Receiving concurrent psychotherapy, social skills training, or behavioral interventions (e.g., applied behavior analysis). Families will have the option of discontinuing such services to enroll in the study.
- Has started an antidepressant within 12 weeks before study enrollment or an antipsychotic 6 weeks before study enrollment.
- Has changed established psychotropic medications (e.g., antidepressants, anxioloytics) within 8 weeks before study enrollment (6 weeks for antipsychotic).
- Is currently suicidal or has been actively suicidal in the last 6 months.
- Has been diagnosed with bipolar, schizophrenia or schizoaffective disorders; or Substance abuse in past 6 months.
- Presence of a significant and/or unstable medical illness which might lead to hospitalization during the study.
Key Trial Info
Start Date :
November 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2014
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT01177969
Start Date
November 1 2009
End Date
April 1 2014
Last Update
July 1 2014
Active Locations (2)
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1
Univeristy of California at Los Angeles
Los Angeles, California, United States
2
University of South Florida
St. Petersburg, Florida, United States, 33701