Status:
COMPLETED
Effect of Supplemental Oral Curcumin in Patients With Atopic Asthma
Lead Sponsor:
University of South Florida
Conditions:
Atopic Asthma
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Curcumin has antioxidant properties and in animal models has numerous molecular targets, many of which are intracellular, such as transcription factors AP-1 and NF. As such, it inhibits the secretion ...
Detailed Description
Research Design This is a randomized, double-blinded, placebo-controlled pilot study to evaluate the effects of oral supplementation of curcumin 2000mg, versus placebo, on patients with a history of s...
Eligibility Criteria
Inclusion
- Males and non-breastfeeding, non-pregnant females
- Aged 18-60 years
- History of physician-diagnosed asthma for 1 year or longer FEV1 60% pre-bronchodilator
- Currently on low or medium dose inhaled corticosteroids (see Appendix 1)
- Use of short-acting β-agonist ≥ 1 in the past 30 days (except for exercise) A ≥ 2+ skin-prick test prick-puncture test to Dermatophagoides pteronyssinus or Dermatophagoidesfarinae with appropriate positive/negative controls (historical is acceptable within 10 years)
Exclusion
Key Trial Info
Start Date :
March 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2010
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT01179256
Start Date
March 1 2009
End Date
March 1 2010
Last Update
August 11 2010
Active Locations (1)
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1
Usf Asthma Allergy and Immunology Cru
Tampa, Florida, United States, 33613