Status:
COMPLETED
Change in Ocular Flora Resistance From Repeated Topical Antibiotic Use
Lead Sponsor:
Sunnybrook Health Sciences Centre
Collaborating Sponsors:
Novartis
Conditions:
Increased Drug Resistance
Infection Resistant to Quinolones and Fluoroquinolones
Eligibility:
All Genders
65+ years
Brief Summary
The purpose of this study is to determine if antibiotic resistance of the ocular surface flora to the 4th generation fluoroquinolones will increase after repeated use of topical antibiotics for three ...
Detailed Description
Treatment with intravitreal (IVT) injections has increased during the last several years as evidence has accumulated demonstrating the efficacy of anti-vascular endothelial growth factor agents in the...
Eligibility Criteria
Inclusion
- patients scheduled for intravitreal injection for neovascular age-related macular degeneration (ARMD)
- 65 years or older
- able to provide informed consent.
Exclusion
- diagnosed with an active ocular, periocular or systemic infection
- previously received treatment with an intravitreal injection
- previously treated with antibiotics in the past three months
- unable to attend the scheduled follow-up appointments or to complete treatment for any reason
Key Trial Info
Start Date :
June 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2011
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT01181713
Start Date
June 1 2010
End Date
December 1 2011
Last Update
March 18 2021
Active Locations (1)
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1
Sunnybrook Health and Sciences Centre
Toronto, Ontario, Canada, M4N 3M5