Status:
COMPLETED
The Effect of Prior Muscle Activation on the Compound Muscle Action Potential (CMAP)
Lead Sponsor:
Loma Linda University
Conditions:
Focus: Effect of Muscle Activation on CMAP in Normal Humans
Eligibility:
All Genders
18-49 years
Phase:
NA
Brief Summary
The purpose of this investigator-initiated study is to determine the effect of prior muscle activation on the response obtained by nerve conduction studies (the compound muscle action potential \[CMAP...
Detailed Description
Nerve conduction studies (NCS) will be performed with supramaximal nerve stimulation, surface stimulation, surface recording, and with best possible technique controlling as many variables as possible...
Eligibility Criteria
Inclusion
- Normal, healthy volunteers
- Age 18-49
Exclusion
- Localized or generalized neuromuscular disorder
- History of neuropathy
- History of diabetes
- History of prior injuries or surgeries of the back, neck, or limbs to be tested which in the opinion of the investigator might have the potential to influence the compound muscle action potential
- Medications other than eyedrops or non-steroidal anti-inflammatory agents (as needed) or contraceptive agents or non-steroidal topical agents
- Abnormalities by screening nerve conduction studies
- Anomalous innervation of the tested extensor digitorum brevis via screening nerve conduction studies
- Use of caffeine or nicotine within 8 hours of testing
Key Trial Info
Start Date :
October 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2019
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT01182558
Start Date
October 1 2010
End Date
August 1 2019
Last Update
August 14 2019
Active Locations (1)
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1
Neurology - Faculty Physicians and Surgeons of Loma Linda University School of Medicine
Loma Linda, California, United States, 92354