Status:
UNKNOWN
Trial of Proton Versus Carbon Ion Radiation Therapy in Patients With Low and Inter-mediate Grade Chondrosarcoma of the Skull Base
Lead Sponsor:
Heidelberg University
Conditions:
Chondrosarcoma
Eligibility:
All Genders
18-80 years
Phase:
PHASE3
Brief Summary
The study is a prospective randomised clinical phase III trial. Proton therapy is the gold standard in the treatment of low and intermediate grad chondrosarcomas of the skull base. However, high-LET b...
Detailed Description
The study is a prospective randomised clinical phase III trial. The trial will be carried out at Heidelberger Ionenstrahl-Therapie (HIT) centre as monocentric trial. Proton therapy is the gold standa...
Eligibility Criteria
Inclusion
- Karnofsky Performance Score ≥60%
- Age \>18 years and \<80 years
- Informed consent signed by the patient
- Histological confirmation of low/ intermediate grade chondrosarcoma with infiltration of the skull base.
Exclusion
- Inability to understand the aims of the study, no informed consent
- Prior RT of skull base region
- Other malignancies with disease-free interval \< 5 years (excepting pre-cancerous lesions)
- Participation in another trial
- Pregnancy
- Simultaneous CHT or Immunotherapy.
Key Trial Info
Start Date :
August 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2022
Estimated Enrollment :
154 Patients enrolled
Trial Details
Trial ID
NCT01182753
Start Date
August 1 2010
End Date
August 1 2022
Last Update
August 17 2010
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Heidelberg
Heidelberg, Im Neuenheimer Feld 400, Germany, 69120