Status:
COMPLETED
Hospital Insulin Protocol Aims for Glucose Control in Corticosteroid-induced Hyperglycemia
Lead Sponsor:
HealthPartners Institute
Collaborating Sponsors:
International Diabetes Center at Park Nicollet
Sanofi
Conditions:
Hyperglycemia
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The objective of this study is to determine the best insulin regimen for hospitalized patients who receive high doses of steroids who have high blood glucose.
Detailed Description
The overall study objective of this research is to establish the efficacy and assure the safety of achieving glycemic control in hospitalized patients who receive greater than physiologic doses of ste...
Eligibility Criteria
Inclusion
- Men or women aged ≥18 years who receive steroids in doses greater than physiologic replacement levels of ≥ 10 mg Prednisone or its equivalent of dexamethasone or methylprednisolone.
- Have signed the consent form for the study
- Have a BG \> 180 mg/dL any time during the first 24 hour of steroid administration that is above physiological replacement ( ≥ 10 mg Prednisone or equivalent)
- Are scheduled to be in hospital ≥ 2 days.
Exclusion
- Unable to read or understand English
- History of psychiatric disability affecting informed consent or compliance with drug intake
- Type 1 diabetes
- Acute or chronic renal failure (creatinine clearance \< 30 mL/min estimated by method of Cockcroft and Gault)
- Patients in Hospice Care
- Age \<18 years
- Previously enrolled in this study.
- Not appropriate for the steroid protocol in judgment of the principal investigator and/or attending physician.
Key Trial Info
Start Date :
August 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2012
Estimated Enrollment :
72 Patients enrolled
Trial Details
Trial ID
NCT01184014
Start Date
August 1 2010
End Date
August 1 2012
Last Update
June 13 2018
Active Locations (1)
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1
Park Nicollet Health Services Methodist Hospital
Saint Louis Park, Minnesota, United States, 55416