Status:

COMPLETED

Randomized Trial of Alternative HPV Vaccination Schedules in Males in a University Setting

Lead Sponsor:

University of Pittsburgh

Collaborating Sponsors:

Merck Sharp & Dohme LLC

Conditions:

Quadrivalent HPV Vaccine

Human Papillomavirus Vaccine

Eligibility:

MALE

18-26 years

Phase:

NA

Brief Summary

The investigators propose a randomized, open label trial of the immunogenicity of HPV vaccine among males 18-24 years old, comparing an on-time administration of the third dose with delayed administra...

Detailed Description

1\. Specific Aims and Overview: The investigators propose a randomized, open label trial of HPV vaccine among males 18-24 years old, comparing an on-time administration of the third dose with delayed ...

Eligibility Criteria

Inclusion

  • Males age 18-26

Exclusion

  • Hospitalization within the past year
  • Previous HPV vaccination
  • \>/=5 sexual partners (i.e., insertive intercourse) No other drug studies within 30 days of proposed HPV vaccination
  • History of genital warts
  • Immunosuppression
  • Other vaccines within 8 days of proposed HPV vaccination
  • Hypersensitivity to yeast or HPV vaccine components
  • Known autoimmune disorders
  • Receipt of immunoglobulins or blood product within 90 days of enrollment (may defer until 90 days completed)
  • Serious Adverse Reaction to HPV vaccine

Key Trial Info

Start Date :

October 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2012

Estimated Enrollment :

220 Patients enrolled

Trial Details

Trial ID

NCT01184079

Start Date

October 1 2010

End Date

May 1 2012

Last Update

March 27 2014

Active Locations (1)

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University of Pittsburgh

Pittsburgh, Pennsylvania, United States, 15261