Status:

TERMINATED

ChloraPrep Versus Betadine for Elective Knee Replacement Surgery

Lead Sponsor:

Central DuPage Hospital

Conditions:

Arthroplasty, Knee Replacement

Replacement, Total Knee

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

This study will enroll patients who will be receiving primary total knee replacements. Subjects will be randomized into two groups: Betadine surgical scrub preparation and ChloraPrep preparation prior...

Detailed Description

Swabs will be taken over the operative knee by study personnel for a bacterial colony count immediately before surgical site preparation is started, after the surgery prep is complete, and 24 hours po...

Eligibility Criteria

Inclusion

  • Scheduled to undergo primary total knee arthroplasty
  • Age 18 or over

Exclusion

  • Inability to provide informed consent or to comply with study assessments due to cognitive impairment or geographic distance
  • Age 17 or younger
  • Allergies to chlorhexadine gluconate or povidone iodine
  • Topical antimicrobial use within 14 days of surgery
  • Any active dermatoses or open wounds over the operative site
  • Any condition requiring antibiotics 14 days prior to arriving for surgery
  • Patients with chronic immunosuppression (such as HIV/AIDS)
  • Unable to adhere to follow up schedule and treatment

Key Trial Info

Start Date :

November 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2012

Estimated Enrollment :

55 Patients enrolled

Trial Details

Trial ID

NCT01184196

Start Date

November 1 2009

End Date

December 1 2012

Last Update

April 16 2013

Active Locations (1)

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Central DuPage Hospital

Winfield, Illinois, United States, 60190