Status:

TERMINATED

Investigating the Role of Impella 2.5 System in Acutely Decompensated Chronic Heart Failure Patients

Lead Sponsor:

Abiomed Inc.

Collaborating Sponsors:

McGill University Health Centre/Research Institute of the McGill University Health Centre

Conditions:

Heart Failure

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

The primary objective of this study is to assess safety and feasibility of IMPELLA 2.5 in Acute Decompensated Heart Failure patients.

Eligibility Criteria

Inclusion

  • Major
  • Chronic heart failure patients, hospitalized due to decompensated heart failure (ADHF) with NYHA Class III-IV symptoms (ADHF is defined by the presence of at least one of the following symptoms/signs: dyspnea w/orthopnea, jugular venous distension, peripheral edema +2, abdominal ascites, signs of CHF on chest X-Ray)
  • LVEF ≤ 40 % within the past 3 months
  • Major

Exclusion

  • Acute Q-wave myocardial infarction or Acute coronary syndrome within past 30 days
  • Cardiac surgery within the past 30 days
  • Implantation of cardiac resynchronization device within past 30 days or a possibility of implanting a biventricular pacer within 90 days of randomization

Key Trial Info

Start Date :

July 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2012

Estimated Enrollment :

1 Patients enrolled

Trial Details

Trial ID

NCT01185691

Start Date

July 1 2010

End Date

December 1 2012

Last Update

May 3 2013

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Investigating the Role of Impella 2.5 System in Acutely Decompensated Chronic Heart Failure Patients | DecenTrialz