Status:
COMPLETED
Effect on Adrenal Function of Budesonide Versus Fluticasone in Chronic Obstructive Pulmonary Disease (COPD)
Lead Sponsor:
Hull University Teaching Hospitals NHS Trust
Conditions:
Chronic Obstructive Pulmonary Disease
Eligibility:
All Genders
18-85 years
Phase:
PHASE4
Brief Summary
National Institute for Clinical Excellence (NICE) guidelines recommend high dose inhaled steroids for patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD, a common chronic dis...
Detailed Description
Background COPD is a very common disease which is chronic and progressive. Current NICE guidelines recommend the use of inhaled steroid in relatively high dose in patients with moderate to severe dise...
Eligibility Criteria
Inclusion
- Patients with a diagnosis of COPD.
- Criteria for treatment with inhaled steroids met as per NICE guidelines.
- Patients on treatment with either Symbicort® or Seretide® at the time of recruitment (on treatment dose as per NICE guidelines).
- Recruited patients are able to understand and co-operate with the study conduct and are willing to give written consent.
Exclusion
- Patients with any concomitant disease which may interfere with the study procedure or evaluation.(self explanatory)
- A recent exacerbation of COPD within the last 8 weeks.( will interfere with assessment )
- Use of oral steroids within the last 2 months.(will interfere with assessment)
- Use of ocular, intra-articular, rectal or other steroids during 4 weeks prior to inclusion.(will interfere with assessment)
- Participation in any other study (use of investigational product) within 4 weeks prior to inclusion.(potential to interfere with assessment)
- Alcohol or drug abuse.(will interfere with assessment)
- Inability to follow study procedures.(self explanatory)
Key Trial Info
Start Date :
October 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2010
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT01186653
Start Date
October 1 2007
End Date
May 1 2010
Last Update
September 6 2010
Active Locations (1)
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1
Respiratory Medicine, Castgle Hill Hospital
Cottingham, East Yorkshire, United Kingdom, HU16 5JQ