Status:
COMPLETED
Study of Cobalt's Role in Excessive Erythrocytosis Among High Altitude Dwellers in Cerro de Pasco, Peru
Lead Sponsor:
University of Colorado, Denver
Collaborating Sponsors:
Universidad Peruana Cayetano Heredia
Jackson, Brian, M.S.
Conditions:
Erythrocytosis
Mountain Sickness
Eligibility:
MALE
18+ years
Phase:
PHASE1
PHASE2
Brief Summary
Chronic mountain sickness is characterized by excessive red blood cell production which causes sludging of the vascular system. This high viscosity blood causes heart failure, cognitive dysfunction, a...
Eligibility Criteria
Inclusion
- Males over 17 years of age
- Hematocrit \> 70%
- Chronic Mountain Sickness score (CMS) \> 6
- Able to give informed consent and follow instructions in written Spanish
Exclusion
- CMS \> 15
- Underlying lung disease, smoking, or oxygen therapy
- Asthma (bronchospasm can be caused by N-acetylcysteine)
- Phlebotomy in last 3 months
- h/o adverse reaction to acetazolamide or N-acetylcysteine
Key Trial Info
Start Date :
June 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2013
Estimated Enrollment :
85 Patients enrolled
Trial Details
Trial ID
NCT01187108
Start Date
June 1 2013
End Date
September 1 2013
Last Update
May 15 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Chronic mountain sickness clinic
Cerro de Pasco, Departamento de Pasco, Peru