Status:
UNKNOWN
Short Non-coding RNA Biomarkers of Predisposition to Ovarian Cancer
Lead Sponsor:
University of Virginia
Conditions:
Ovarian Cancer
Eligibility:
FEMALE
18-90 years
Brief Summary
The purpose of this study is to create new tests to identify biomarkers for ovarian cancer so that a screening test can be developed. For patients who have a diagnosis of ovarian Cancer, researchers w...
Detailed Description
Epithelial ovarian cancer is the most lethal female reproductive malignancy, mainly because 80% of tumors have metastasized beyond the ovary at the time of diagnosis. Screening efforts aimed at improv...
Eligibility Criteria
Inclusion
- Undergoing medical care at UVA
- Up to date breast cancer screening
- Subjects must fall into one of the following groups:
- Women at increased risk of ovarian cancer based on family history, personal history, or genetic factors defined as either BRCA1 or BRCA2 mutations who still retain both fallopian tubes and both ovaries.
- Women at average risk for ovarian cancer
- Women with known/suspected or recurrent ovarian cancer who are undergoing evaluation and/or treatment at UVA Cancer Center
Exclusion
- Subjects with increased risk for ovarian cancer may not have a history of prior malignancy within the last 10 years excluding cervical carcinoma in situ or basal cell carcinoma
- Pregnancy (self reported)
Key Trial Info
Start Date :
August 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2015
Estimated Enrollment :
103 Patients enrolled
Trial Details
Trial ID
NCT01187602
Start Date
August 1 2010
End Date
June 1 2015
Last Update
December 5 2014
Active Locations (1)
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1
University of Virginia
Charlottesville, Virginia, United States, 22908