Status:
COMPLETED
Metformin to Prevent Metabolic Complications in Glucocorticoid Excess
Lead Sponsor:
University Hospital, Basel, Switzerland
Conditions:
Patients With Glucocorticoid Treatment
Eligibility:
All Genders
18-100 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to evaluate if a treatment with metformin compared to placebo reduces metabolic side-effects in patients with glucocorticoid treatment over three months time.
Eligibility Criteria
Inclusion
- Glucocorticoid treatment for ≥ 3 months with a prednisone dose of ≥ 7.5mg/d or equivalent glucocorticoid
Exclusion
- Refusal of informed consent
- Prior therapy with metformin during the last 6 month
- Preexisting diabetes
- Pregnancy or current malignancy
- Renal insufficiency with a creatinine clearance lower than 30ml/min
Key Trial Info
Start Date :
August 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2015
Estimated Enrollment :
29 Patients enrolled
Trial Details
Trial ID
NCT01187849
Start Date
August 1 2010
End Date
December 1 2015
Last Update
April 28 2016
Active Locations (1)
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1
University Hospital Basel
Basel, Canton of Basel-City, Switzerland, 4031