Status:

COMPLETED

Pharmacokinetic Study to Characterize Individual Metabolic Profile

Lead Sponsor:

Institut National de la Santé Et de la Recherche Médicale, France

Collaborating Sponsors:

Nuclear Energy Commission (CEA)

Conditions:

Healthy Volunteers

Eligibility:

All Genders

18-45 years

Phase:

PHASE1

Brief Summary

The study aims to descibe the pharmacokinetics of 10 substrates of enzymes involved in drug metabolism and their metabolites, after administration singly and simultaenously at predefined doses in 10 h...

Detailed Description

The aim of this study is to test the administration of combination of substrates and thereby to characterise simultaneously the main enzymes and transporters involved in drug metabolism. The doses of ...

Eligibility Criteria

Inclusion

  • healthy volunteers

Exclusion

  • pregnancy

Key Trial Info

Start Date :

August 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2011

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT01188525

Start Date

August 1 2010

End Date

July 1 2011

Last Update

September 3 2025

Active Locations (1)

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1

Center of clinical investigation

Paris, France, 75018