Status:
COMPLETED
Efficacy of Exercise for Sexual Side Effects of Antidepressants
Lead Sponsor:
University of Texas at Austin
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Sexual Dysfunction
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
The major aim of the this study is to replicate findings of previous research that examined the effects of acute exercise on sexual arousal in women in a novel population, namely, women taking antidep...
Eligibility Criteria
Inclusion
- female
- age 18 or older
- currently receiving a consistent dosage of escitalopram, citalopram, sertraline, desvenlafaxine, venlafaxine, or duloxetine
- currently sexually active
- willing and able to exercise
- experiencing regular menstrual cycles
- not currently pregnant and not intending to become pregnant during trial
Exclusion
- currently taking more than one psychoactive medication
- factors indicating risk of cardiovascular activity, including acute or chronic cardiovascular illness, including clinically significant hypertension (defined as self-reported hypertension or "blood pressure greater than 140/90" or receiving medications designed to treat hypertension); recent chest pain; frequent or recurrent faint or dizzy spells; severe or untreated exercise-related asthma; or musculoskeletal illness or injury that would be expected to worsen with physical exercise. Additionally, women will be excluded if they are found to have any of the following as measured during the fitness assessment of the first session: a BMI over 40, waist circumference over 40 inches, waist-to-hip ratio of greater than 0.9, systolic blood pressure greater than 150 or diastolic pressure over 95, or resting heart rate over 90.
- factors associated with significant genital nerve damage, including: previous major pelvic surgery that may have caused nerve damage, including hysterectomy, vulvectomy, circumcision, colostomy, cystostomy, or serious bladder, rectal, or abdominal surgery; or neurological impairment due to diabetes, stroke, pelvic nerve damage secondary to trauma, cancer treatments, myasthenia gravis, multiple sclerosis or spinal cord damage.
- factors associated with non-normative endocrine function, including: perimenopausal or menopausal status, or \>1 missed menstrual period in the previous 6 months; or currently pregnant, breastfeeding, or having breastfed within the past 3 months; or reporting clinically significant untreated renal or endocrine disease
- untreated serious mental health conditions
- sexual aversion or distress due to history of unwanted sexual contact
Key Trial Info
Start Date :
June 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2012
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT01189825
Start Date
June 1 2009
End Date
August 1 2012
Last Update
February 27 2013
Active Locations (1)
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1
University of Texas at Austin
Austin, Texas, United States, 78712