Status:

COMPLETED

Characterization of Rectal Cancer Hypoxia Using pO2 Histography and Immunohistochemistry for Hypoxia-Related Proteins

Lead Sponsor:

Memorial Sloan Kettering Cancer Center

Conditions:

Rectal Cancer

Eligibility:

All Genders

18-89 years

Phase:

NA

Brief Summary

The purpose of this study is to see if the cells in rectal cancer are oxygen-starved, or hypoxic. We know that as cancers grow bigger, parts of them are cut off from the oxygen supply and they become ...

Eligibility Criteria

Inclusion

  • Biopsy proven adenocarcinoma of the rectum. If a biopsy was taken at an outside hospital, the slides and diagnosis will be reviewed and confirmed by a pathologist at MSKCC.
  • Mid to distal rectal tumors not requiring pre-op radiation or chemotherapy
  • Age ≥ 18
  • Age \< 90
  • Karnofsky performance status ≥ 60
  • Ability to understand and the willingness to sign a written informed consent document.

Exclusion

  • Current pregnancy
  • Uncontrolled intercurrent illness that would limit compliance with study requirements.

Key Trial Info

Start Date :

August 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2012

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT01189877

Start Date

August 1 2010

End Date

October 1 2012

Last Update

October 11 2012

Active Locations (1)

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1

Memorial Sloan Kettering Cancer Center

New York, New York, United States, 10065