Status:
COMPLETED
Arterial Stiffness Index as a Predictor of Surgically Correctable Primary Aldosteronism
Lead Sponsor:
University Hospital, Toulouse
Conditions:
Adenoma
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Our main objective is to assess whether aortic stiffness is a predictor of blood pressure response after surgery in patients with an aldosterone producing adenoma or a unilateral adrenal hyperplasia.
Detailed Description
Secondary objectives are to investigate whether aortic stiffness predicts cardiovascular , operative and postoperative morbid-mortality at 1 year, to evaluate the benefit of adrenalectomy in patients ...
Eligibility Criteria
Inclusion
- patients with a surgically correctable primary aldosteronism due to an aldosterone producing adenoma or an unilateral adrenal hyperplasia
- primary aldosteronism demonstrated by hormonal essays
- hight resolution adrenal CT scan
- operative decision based on the usual criteria of the different referent centers
Exclusion
- patient's refusal to undergo the surgery or to participate in the study
- the patients with PA due to bilateral adrenal hyperplasia or with idiopathic primary aldosteronism, and patients with a biochemical diagnosis of PA without evidence for a lateralized aldosterone excess.
Key Trial Info
Start Date :
June 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2015
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT01190501
Start Date
June 1 2009
End Date
June 1 2015
Last Update
February 23 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
CHU Toulouse
Toulouse, France, 31059